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Vivitrol Side Effects

Commonly reported reactions to Vivitrol include headache, fatigue, and diarrhea. Although it is difficult to predict if you will develop side effects while using Vivitrol, it's important to know that this prescription medicine can cause potentially serious problems. Make sure to seek medical attention right away if you experience blurred vision, thoughts of suicide, or breathing problems.

An Introduction to Vivitrol Side Effects

As with any medicine, Vivitrol® (naltrexone injection) can cause side effects. However, not everyone who uses the medication will experience problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Vivitrol. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects With Vivitrol

Vivitrol has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people receiving Vivitrol were carefully documented and compared with the side effects that occurred in a similar group of people receiving a placebo (an injection with no active ingredient). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared with the placebo.
In these studies, common Vivitrol side effects included:
  • Injection site reactions -- in up to 65 percent of people
  • Nausea (especially after the first injection) -- up to 29 percent
  • Headache -- up to 21 percent
  • Fatigue -- up to 20 percent
  • Diarrhea -- up to 13 percent
  • Symptoms of the common cold, such as a sore throat, coughing, and a runny nose -- up to 13 percent
  • Insomnia -- up to 13 percent
  • Dizziness or fainting -- up to 13 percent
  • Increases in liver enzymes -- up to 13 percent
  • Vomiting -- up to 12 percent
  • Abdominal (stomach) pain -- up to 11 percent
  • Decreased appetite -- up to 11 percent.
Injection site reactions included the following:
  • Tenderness
  • Hardening of the skin
  • Pain
  • Swelling
  • Bruising
  • Itching.
Other common side effects, occurring in 3 percent to 10 percent of people, included:
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Vivitrol Medication Information

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