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Drug Interactions With Vilazodone

Antipsychotic Medications
Taking vilazodone with antipsychotics may increase your risk for a rare but potentially dangerous group of symptoms. These symptoms may include increased body temperature, extreme confusion, disorientation, and stiff muscles that are difficult to move. Talk to your healthcare provider about this potential interaction. Contact your healthcare provider right away if you experience any of these symptoms (see Precautions and Warnings With Vilazodone).
 
Atomoxetine
Taking vilazodone with atomoxetine may increase your risk for a serious reaction called serotonin syndrome. Although this reaction is extremely rare, it can be dangerous. Talk to your healthcare provider before taking these medications together. Contact your healthcare provider right away if you experience symptoms of serotonin syndrome (see Precautions and Warnings With Vilazodone).
 
Buspirone
Taking vilazodone with buspirone may increase your risk for a serious reaction called serotonin syndrome. Although this reaction is quite rare, it can be dangerous. Talk to your healthcare provider before taking these medications together. Also, seek immediate medical care if you develop any symptoms of serotonin syndrome (see Precautions and Warnings With Vilazodone).
 
CYP 3A4 Inducer Medications
The body breaks down vilazodone using enzymes in the liver known as CYP 3A4 enzymes. Medications known as CYP 3A4 inducers can increase the activity of these enzymes. Combining vilazodone with one of these drugs may decrease the level of vilazodone in your body. Your healthcare provider may monitor you more closely to make sure vilazodone is working to treat your depression if you take it with a CYP 3A4 inducer.
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Vilazodone Drug Information

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