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Trazodone ER

Drug Interactions

Trazodone ER can potentially interact with several other medicines (see Drug Interactions With Trazodone ER).

What If I Take an Overdose?

An overdose with trazodone ER can lead to life-threatening complications. If you happen to overdose on this medication, seek immediate medical attention.
(Click Oleptro Overdose for more information.)

What Should I Do If I Miss a Dose?

If you do not take your trazodone ER as scheduled, take your missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose of the medication. Because trazodone ER should be taken in the late evening (preferably at bedtime), you may want to consider skipping missed doses, instead of taking it during the day (as taking it during the day might cause excessive daytime drowsiness).

How Does Trazodone ER Work?

It is not entirely clear how trazodone ER works. There are no other medications that work exactly like it (other than the short-acting version of trazodone). It is known that trazodone ER acts on a specific chemical within the brain known as serotonin. Serotonin is one of several chemicals used to send messages in between the nerves; but, when serotonin levels become unbalanced, it can cause a variety of conditions, including depression.
Trazodone ER helps to block the reuptake of serotonin (so that more serotonin is available for the nerves in the brain), which returns serotonin back to its "normal" levels. However, unlike selective serotonin reuptake inhibitors (SSRIs), trazodone may also block certain serotonin receptors.
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Trazodone ER Drug Information

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