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Drug Interactions With Trazodone ER

St. John's Wort
Taking trazodone ER with St. John's wort can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see Precautions and Warnings With Trazodone ER), as it can be very dangerous.
 
Tramadol
Taking trazodone ER with tramadol can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see Precautions and Warnings With Trazodone ER), as it can be very dangerous.
 
Tricyclic Antidepressants
Taking trazodone ER with tricyclic antidepressants can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see Precautions and Warnings With Trazodone ER), as it can be very dangerous.
 
Triptans
Taking trazodone ER with a triptan can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see Precautions and Warnings With Trazodone ER), as it can be very dangerous.
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Trazodone ER Drug Information

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