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How Does Thorazine Work?

As mentioned, Thorazine belongs to a group of medications called typical (or first-generation) antipsychotic medications. In particular, it is part of a group of medications called phenothiazines. It is not entirely known precisely how this medication works. However, it is known to block or lessen the effects of dopamine, a chemical in the brain. Dopamine may be elevated in people with schizophrenia.
Thorazine is not a cure for schizophrenia. It only helps to control symptoms (see Symptoms of Schizophrenia).
Since dopamine can activate the part of the brain that controls nausea and vomiting, Thorazine can treat severe nausea and vomiting by lessening the effects of dopamine in the brain.

When and How to Take It

The following are some general considerations for when and how to take Thorazine:
  • The medication comes in tablet form. It is usually taken by mouth one to six times daily.
  • You can take the medication with or without food. If Thorazine bothers your stomach, try taking it with food.
  • Thorazine should be taken at the same time(s) each day to maintain an even level in your blood.
  • For Thorazine to work properly, it must be taken as prescribed. The medication will not work if you stop taking it.

Dosing Information

The dose of Thorazine your healthcare provider recommends will vary, depending on a number of factors, including:
  • The medical condition being treated
  • Your age and weight
  • Other medical conditions you may have
  • Other medications you may be taking.
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Thorazine Dosage for more information.)
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Thorazine Medication

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