Drug Interactions With Thiothixene (Cont.)

 
Antacids
Antacids can interfere with the absorption of thiothixene into your bloodstream. To avoid this problem, be sure to take thiothixene at least one hour before or two hours after an antacid dose.
 
Apomorphine (Apokyn)
Thiothixene may decrease the effectiveness of medications for Parkinson's disease, including apomorphine. Talk with your healthcare provider before taking these medications together.
 
Bromocriptine (Parlodel)
Thiothixene may decrease the effectiveness of medications for Parkinson's disease, including bromocriptine. Talk with your healthcare provider before taking these medications together.
 
Carbamazepine (Epitol, Equetro, Tegretol, Tegretol XR)
Carbamazepine can decrease the level of thiothixene in your blood, perhaps making it less effective. If you are taking these drugs together, your healthcare provider may need to increase your thiothixene dosage.
 
Fluoxetine (Prozac, Sarafem, Symbyax)
Fluoxetine can raise the level of thiothixene in your blood, increasing your risk of side effects. If you are taking these drugs together, your healthcare provider may need to decrease your thiothixene dosage.
 
Levodopa-Containing Medications (Parcopa, Sinemet, Stalevo)
Thiothixene may decrease the effectiveness of medications for Parkinson's disease, including levodopa products. Talk with your healthcare provider before taking these medications together.
 
Paroxetine (Paxil, Paxil CR)
Paroxetine can raise the level of thiothixene in your blood, increasing your risk of side effects. If you are taking these drugs together, your healthcare provider may need to decrease your thiothixene dosage.
(Drug Interactions With Thiothixene Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;