Benefits of SAM-e
It is not clear exactly how SAM-e works for depression treatment or other uses. SAM-e causes several changes in the brain that may be responsible for its antidepressant effects.
SAM-e probably works in several different ways for arthritis treatment. It may have pain-relieving and anti-inflammatory effects, and may stimulate the growth and repair of cartilage in joints.
People with intrahepatic cholestasis often have a decreased ability to make SAM-e, which can cause numerous problems and can further worsen liver problems. SAM-e supplements can help make up for this decrease in production.
SAM-e may work for AIDS-related myelopathy because SAM-e levels in the spinal fluid of people with AIDS are often low.
Since children may be more susceptible to toxicities of dietary supplements, do not give your child any supplement, including SAM-e, without discussing it with your child's healthcare provider.