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Side Effects of Quetiapine XR

Side Effects of Quetiapine XR to Report

There are a number of side effects with quetiapine XR that you should report to your healthcare provider right away. These include, but are not limited to:
  • Signs of diabetes, such as high blood sugar, increased thirst, frequent urination, and/or extreme hunger (see Seroquel and Diabetes)
  • A large or rapid weight gain (see Seroquel XR and Weight Gain)
  • Signs of low white blood cells, such as frequent or persistent infections
  • Seizures
  • High triglycerides or high cholesterol 
  • Suicidal thoughts
  • Dizziness or fainting when going from a sitting or lying-down position to standing
  • Feelings of internal restlessness or jitteriness
  • Any abnormal muscle movements (these abnormal movements can become permanent if quetiapine XR is not stopped quickly)
  • A painful erection of the penis that does not go away (this can cause permanent damage to the penis)
  • Signs or symptoms of neuroleptic malignant syndrome (NMS), which can include:
o A high fever
o Stiff muscles
o Confusion
o An irregular pulse or blood pressure
o An increased heart rate (tachycardia)
o Sweating
o Irregular heart rhythms (arrhythmias) 
  • Signs of an allergic reaction, including an unexplained rash, hives, itching, unexplained swelling, wheezing, or difficulty breathing or swallowing.

Less Common Side Effects of Quetiapine XR

There are other, less common quetiapine XR side effects that can occur. These side effects occur in less than 5 percent of people taking quetiapine XR. For these side effects, it is difficult to tell whether the side effect is caused by quetiapine XR or other factors.
These less common quetiapine XR side effects include, but are not limited to:
  • Shakiness (tremors)
  • Fever
  • Blurred vision
  • Drooling
  • Swallowing problems.
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