Quetiapine XR Dosing

The recommended starting quetiapine XR dosage for treating schizophrenia is 300 mg once daily, typically taken in the evening. If necessary, your healthcare provider will increase your dose within a few days. The maximum quetiapine XR dose is 800 mg per day. Among the factors that can affect quetiapine XR dosing are the severity of your schizophrenia and other conditions you may have.

 

An Introduction to Quetiapine XR Dosing

The dose of quetiapine XR (Seroquel XR®) your healthcare provider recommends will vary depending on a number of factors, including:
 
  • The severity of your condition
  • Other medical conditions you may have
  • Other medications you may currently be taking.
     
As always, do not adjust your quetiapine XR dose unless your healthcare provider specifically instructs you to do so.
 

Quetiapine XR Dosing for Schizophrenia

The recommended starting quetiapine XR dose for treating schizophrenia is quetiapine XR 300 mg once daily, preferably in the evening. Generally, your healthcare provider will increase your dose quickly within a few days, up to quetiapine XR 800 mg once daily if needed.
 

General Quetiapine XR Dosing Information

Some considerations for people taking quetiapine XR include:
 
 
  • Quetiapine XR comes in tablet form. It is usually taken by mouth once a day, typically in the evening.
     
  • While quetiapine XR can be taken on an empty stomach or with a light meal (300 calories or less), it should not be taken with a large, fatty meal. Taking quetiapine XR with too much food can increase the amount of quetiapine XR in your blood, increasing your risk of side effects.
     
  • Quetiapine XR tablets are extended release and should not be crushed, split, broken, or chewed. They should be swallowed whole.
     
  • Quetiapine XR should be taken at the same time each day to maintain even levels of the drug in your blood.
     
  • For quetiapine XR to work properly, it must be taken as prescribed. Quetiapine XR will not work if you stop taking it.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;