Drug Interactions With Quetiapine XR

Drug interactions with quetiapine XR can potentially occur when the drug is taken with certain other medications, such as lorazepam, some antibiotic medications, and cimetidine. Some of these interactions can lead to problems such as increased or decreased drug levels in the blood, an increased risk of side effects, or reduced effectiveness of the drugs. Before taking quetiapine XR, be sure to talk with your pharmacist or healthcare provider about any drug interactions that may apply to you.

 

An Introduction to Drug Interactions With Quetiapine XR

Quetiapine XR (Seroquel XR®) can potentially interact with several other medications. Some of these medicines that may lead to quetiapine XR interactions include:
 
  • Alcoholic beverages
  • Certain antibiotics or antifungals, including:
o Clarithromycin (Biaxin®)
o Erythromycin (Ery-Tab®)
o Isoniazid (Nydrazid®)
o Itraconazole (Sporanox®)
o Ketoconazole (Nizoral®)
o Telithromycin (Ketek®) 
 

Quetiapine XR Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when quetiapine XR is combined with any of the drugs listed above.
 
Alcoholic Beverages
It is not recommended that you drink alcohol while taking quetiapine XR. Taking alcohol and quetiapine XR together may cause unwanted side effects (see Alcohol and Seroquel).
(Drug Interactions With Quetiapine XR Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;