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Drug Interactions With Phenelzine

There are a number of dangerous and potentially life-threatening drug interactions with phenelzine, so tell your healthcare provider about all other medications you are taking before starting the antidepressant. Medicines that may lead to negative interactions include stimulants, reserpine, blood pressure medications, and atomoxetine. Most drug interactions with phenelzine can increase the risk of dangerously high blood pressure or other serious side effects.

Drug Interactions With Phenelzine: An Introduction

Phenelzine sulfate (Nardil®) can potentially interact with many medicines. Because so many drug interactions with phenelzine can be dangerous, it is important to check with your healthcare provider before taking any medication, whether prescription or over-the-counter. Make sure to tell all your healthcare providers (including dentists and surgeons) that you are taking phenelzine. Some of the medicines that may lead to phenelzine drug interactions include:


    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)





  • Other monoamine oxidase inhibitors (MAOIs), including:




    • Dopamine
    • Ephedrine
    • Epinephrine (Adrenalin®, EpiPen®, Primatene Mist®)
    • Isometheptene (Duradrin®, Midrin®, Migquin®, Migratine®, Migrazone®, Migrin-A®)
    • Levonordefrin (Carbocaine with Neo-Cobefrin®)
    • Midodrine (Orvaten®, ProAmatine®)
    • Norepinephrine (Levophed®)



  • Stimulants, such as:





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Phenelzine Drug Information

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