Precautions and Warnings With Perphenazine

Precautions and warnings with perphenazine should be reviewed prior to taking the medication. For example, it can cause neuroleptic malignant syndrome, a potentially life-threatening condition. Medical conditions to tell your healthcare provider about before taking the drug include kidney disease, a blood disorder, and brain damage. Precautions and warnings with perphenazine also include being aware of possible drug interactions and the safety of taking the medicine while pregnant or nursing.

 

Perphenazine: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking
 perphenazine (Trilafon®) if you have:
 
  • Kidney disease, including kidney failure (renal failure)
  • A blood disorder
  • Brain damage
  • Breathing problems, including infections, asthma, or emphysema
  • Glaucoma
  • Very high or very low blood pressure
  • An enlarged prostate (also known as benign prostatic hyperplasia or BPH)
  • Difficulty passing urine
  • Any allergies, including allergies to food, dyes, or preservatives.
     
Also, let your healthcare provider know if you:
 
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding
  • Have an upcoming surgery
  • Drink alcohol.
     
You should also be sure to tell your healthcare provider about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Precautions and Warnings With Perphenazine Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;