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Side Effects of Paroxetine Mesylate

Common Side Effects

Paroxetine mesylate has been studied thoroughly in clinical trials. In these studies, one group of people received the real medication, while another group was given a placebo (a "sugar pill" with no active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the other medication.
In these studies, the most common paroxetine mesylate side effects included:
  • Nausea -- in up to 26 percent of people
  • Ejaculation problems -- up to 25 percent (see Pexeva and Sexual Side Effects)
  • Insomnia -- up to 24 percent
  • Drowsiness -- up to 24 percent
  • Weakness -- up to 22 percent
  • Dry mouth -- up to 18 percent
  • Headache -- up to 18 percent
  • Constipation -- up to 16 percent
  • Sweating -- up to 14 percent
  • Dizziness -- up to 14 percent
  • Diarrhea -- up to 12 percent
  • Shakiness (tremor) -- up to 11 percent
  • Decreased sex drive (libido) or other sexual side effects -- up to 10 percent.
Other common reactions (occurring in 5 to 9 percent of people) included:

Less Common Paroxetine Mesylate Side Effects

Rare side effects were reported in 2 to 5 percent of people taking the drug. Some of these reactions include but are not limited to:
  • Abdominal pain (stomach pain)
  • Flushing (redness of the skin, especially the face)
  • Gas
  • Tingling, pricking, or numbness of the skin
  • Yawning
  • Blurred vision
  • Increased appetite (see Does Pexeva Cause Weight Gain?)
  • Abnormal dreams
  • Trouble concentrating
  • Chest pain
  • Chills
  • Vomiting
  • Feelings of a rapidly or forcefully beating heart (palpitations)
  • Memory loss (amnesia)
  • Taste changes.
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Paroxetine Mesylate Drug Information

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