Drug Interactions With Paliperidone
Interactions With Paliperidone ExplainedEvery one of the medications listed above (except carbamazepine) increases the risk of a dangerous irregular heart rhythm (arrhythmia) called QT prolongation. Since paliperidone can also increase the risk of QT prolongation, it should generally not be combined with any of the above medications. In some instances, it may be appropriate to use paliperidone with the above medications, especially if the heart is monitored closely. Since this list does not include all QT prolonging medications, it is very important to tell your healthcare provider (prior to taking paliperidone) about every other medication you are taking.
Carbamazepine interacts with paliperidone by decreasing the level of paliperidone in the blood, possibly making it less effective. If you start taking carbamazepine, your paliperidone dose may need to be increased; if you stop taking carbamazepine, your dose may need to be decreased. Make sure to consult your healthcare provider before combining these medications.
It is possible that not every drug interaction with paliperidone was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about specific drug interactions with paliperidone that may apply to you.