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What Is Paliperidone Palmitate Used For?

How Does This Medicine Work?

Paliperidone palmitate belongs to a group of medicines known as atypical antipsychotics (also known as second-generation antipsychotics). It is thought to work by blocking the action of dopamine, a neurotransmitter (chemical) in the brain that is believed to be elevated in people with schizophrenia. Like other atypical antipsychotics, paliperidone palmitate also blocks a type of serotonin (another chemical found in the brain) receptor, which is believed to help control some of the symptoms of schizophrenia.
Paliperidone palmitate is given as an injection into a muscle. After each dose, the medication leaves the body slowly, allowing for once-a-month dosing.

Can Children Use It?

Paliperidone palmitate has not been adequately studied in children and is only approved for adults age 18 and older. Talk with your child's healthcare provider about the particular benefits and risks of using paliperidone palmitate in children.

Is It Safe for Older Adults to Use Paliperidone Palmitate?

Older adults may be more sensitive to certain paliperidone palmitate side effects, including movement disorders. In addition, older adults are more likely to have reduced kidney function and may need a lower-than-normal dose of this medicine.

Is Paliperidone Palmitate Used for Off-Label Reasons?

On occasion, a healthcare provider may recommend this medication for something other than the approved use. This is known as an "off-label" use. Some possible off-label uses for paliperidone palmitate may include the treatment of:
  • Schizoaffective disorder
  • Schizophrenia in people younger than 18 years old.
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Paliperidone Palmitate Drug Information

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