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Paliperidone Palmitate Side Effects

Seek medical attention if you are receiving paliperidone palmitate injections and experience side effects such as a high fever, tremors, or other potentially serious reactions. In most cases, however, reactions to this medicine tend to be minor and easy to treat. Clinical research has shown that headaches, anxiety, and insomnia are some of the most common problems reported with this drug.

An Introduction to Side Effects of Paliperidone Palmitate

Just like any medicine, paliperidone palmitate (Invega® Sustenna®) can cause side effects. However, not everyone who receives the medication will experience problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with paliperidone palmitate. Your healthcare provider can discuss a more complete list with you.)
 

Serious Paliperidone Palmitate Side Effects

Some side effects of paliperidone palmitate are potentially serious and should be reported to your healthcare provider right away. These include but are not limited to:
 
  • Signs of an allergic reaction, such as:
 
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing
 
 
    • Feelings of internal restlessness or an inability to sit still
    • Tremors
    • Involuntary, uncontrollable facial, tongue, or body movements
    • Severe muscle stiffness, tension, or contractions
    • Spasms of the neck muscles
 
  • An abnormal, forceful, or rapidly beating heart
  • Dizziness or fainting, especially when rising from a seated or lying position
  • Weight gain
  • Unexplained breast enlargement or breast discharge
  • Missed menstrual periods
  • Signs of high blood sugar, such as:
 
    • Increased thirst
    • Frequent urination
    • Feeling weak or hungry
 
  • Seizures
  • Throat tightness or difficulty swallowing
  • Anxiety
  • Thoughts of suicide or wanting to harm yourself
  • High blood pressure (hypertension)
  • Unexplained fever or infection
  • A prolonged or painful erection that lasts more than four hours
  • Signs of a serious condition known as neuroleptic malignant syndrome, such as:
 
    • High fever
    • Rigid muscles
    • Shaking
    • Confusion
    • Increased sweating
    • Increased heart rate
    • Increased blood pressure
    • Muscle pain or weakness.
 
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Paliperidone Palmitate Drug Information

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