Drug Interactions With Paliperidone Palmitate

Paliperidone palmitate can interfere with many different products, so make sure your healthcare provider is aware of any other medicine, vitamin, or herbal supplement you are taking before starting treatment. For example, drug interactions may occur when paliperidone palmitate is combined with alcohol, sleep medicines, or certain medications used to treat Parkinson's disease. These interactions could lead to potentially serious side effects or other problems.

An Overview of Paliperidone Palmitate Interactions

 Paliperidone palmitate (Invega® Sustenna®) may interact with a number of other medications. Some of the products that may lead to paliperidone palmitate drug interactions include:
 
 
 
  • Medications that cause a certain change in the heart rhythm known as QT prolongation (see QT-Prolonging Medications for a list of such medications)
  • Medications that cause drowsiness, such as:
 
 
 
 
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Written by/reviewed by: Susan Lakey, PharmD, MPH, BCPP
Last reviewed by: Kristi Monson, PharmD
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