Mental Health Channel
Topics & Medications
Quicklinks
Related Channels

Drug Interactions With Paliperidone Palmitate

More Detail on Drug Interactions With Paliperidone Palmitate

The following sections explain in detail the potentially negative reactions that can occur when paliperidone palmitate is combined with any of the drugs listed above.
 
Alcohol
Drinking alcohol may increase your risk for certain paliperidone palmitate side effects, such as drowsiness, dizziness, or lightheadedness. This could make it unsafe to perform tasks that require mental alertness, such as driving, even if you believe you feel fine.
 
Carbamazepine
Carbamazepine may decrease blood levels of paliperidone palmitate. Your healthcare provider may choose to give you a higher paliperidone palmitate dose if you use it with carbamazepine. In addition, your paliperidone palmitate dosage may need to be adjusted each time your carbamazepine dosage is changed.
 
QT-Prolonging Medications
Paliperidone palmitate may cause a certain change in the heart rhythm known as QT prolongation. Combining this medication with other medicines that can cause QT prolongation increases your risk for this life-threatening arrhythmia. Your healthcare provider may choose to monitor the electrical activity of your heart, using an electrocardiogram (ECG), if you use paliperidone palmitate with another QT-prolonging medication.
 
Medications That Cause Drowsiness
Combining paliperidone palmitate with other medications that cause drowsiness may increase your risk for side effects, such as drowsiness, dizziness, or lightheadedness. This could make it unsafe to perform tasks that require mental alertness, such as driving.
 
Metoclopramide
Combining paliperidone palmitate with metoclopramide could increase your risk for serious movement disorders known as extrapyramidal side effects. It could also increase your risk for neuroleptic malignant syndrome (NMS), a rare but life-threatening neurological disorder associated with antipsychotic use (see Paliperidone Palmitate Side Effects for a list of possible extrapyramidal and NMS symptoms). In general, paliperidone palmitate should not be combined with metoclopramide.
Quick Tips to Reduce Stress

Paliperidone Palmitate Drug Information

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.