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Side Effects of Orally Disintegrating Alprazolam

Common Side Effects

Orally disintegrating alprazolam has been studied extensively in clinical trials. In these studies, one group of people received the real medication, while another group was given a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
In anxiety disorder studies, the most common orally disintegrating alprazolam side effects included:
  • Drowsiness -- in up to 41.0 percent of people
  • Fatigue and tiredness -- up to 48.6 percent
  • Coordination problems -- up to 40.1 percent
  • Irritability -- up to 33.1 percent
  • Memory problems -- up to 33.1 percent
  • Dry mouth -- up to 32.8 percent
  • Appetite or weight changes -- up to 32.7 percent
  • Lightheadedness and dizziness -- up to 29.8 percent
  • Insomnia -- up to 29.4 percent
  • Headaches -- up to 29.2 percent
  • Problems thinking -- up to 28.8 percent
  • Constipation -- up to 26.2 percent
  • Distorted, slurred, or slow speech -- up to 23.3 percent
  • Nausea and vomiting -- up to 22.0 percent
  • Blurred vision -- up to 21.0 percent
  • Diarrhea -- up to 20.6 percent.
Other common reactions, occurring in 1 to 20 percent of people, included:
  • Depression
  • Confusion
  • A rapidly or forcefully beating heart
  • Nasal congestion
  • Low blood pressure
  • Increased saliva production
  • Nervousness
  • Tremors
  • Skin redness or rash
  • Fainting
  • An unpleasant feeling of inner restlessness
  • Indigestion or heartburn
  • Anxiety
  • Increased heart rate
  • Sweating
  • Abnormal unintentional movements, such as tremors, twitching, or jerking
  • Sexual problems, such as changes in sex drive (libido) or impotence (erectile dysfunction or ED)
  • Problems urinating
  • Chest pain
  • Menstrual problems
  • Rapid, deep breathing
  • Weakness
  • Ringing in the ears
  • Swelling in the arms, hands, legs, ankles, or feet
  • Upper respiratory infections, such as the common cold
  • Loss of inhibition
  • Feeling of tingling, pricking, or numbness
  • Muscle stiffness or cramps
  • Talkativeness
  • Feelings of unreality (feeling like surroundings are not real)
  • Abnormal dreams
  • Involuntary urine leakage (incontinence)
  • Feelings of fear
  • Feeling warm
  • Infection.
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Orally Disintegrating Alprazolam Information

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