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Norpramin Warnings and Precautions

Some Precautions and Warnings With Norpramin

Some Norpramin warnings and precautions to be aware of include:
  • Antidepressants (including Norpramin) may increase the risk of suicidal thinking or behavior in children, teenagers, and adults (see Antidepressants and Suicide for more information). Therefore, if you notice any changes in symptoms or new symptoms while taking Norpramin, talk with your healthcare provider immediately. Some of these symptoms may include anxiety, hostility, agitation, panic, restlessness, hallucinations, extreme hyperactivity, and suicidal thinking or behavior (see Desipramine and Suicide for more information).
  • Before prescribing Norpramin for depression, your healthcare provider should make sure that you do not have bipolar disorder (instead of depression). The symptoms of bipolar disorder and depression are sometimes very similar, and Norpramin can cause problems in people with bipolar disorder.
  • Norpramin may worsen schizophrenia. Discuss this risk with your healthcare provider before taking Norpramin.
  • People taking Norpramin should use caution when driving, operating heavy machinery, or performing other tasks that require concentration -- especially when first starting the medicine or when switching dosages. This is because Norpramin may affect a person's mental or physical ability to perform these tasks. Make sure to understand how Norpramin affects you before performing any tasks that require mental or physical concentration.
  • Norpramin can interact with certain other medications (see Norpramin Drug Interactions).
  • Norpramin may enhance the effects of alcohol, barbiturates, and other medicines that affect the brain. This can lead to an increased risk of drowsiness, dizziness, suicidal thoughts, and other Norpramin overdose symptoms. Make sure to talk with your healthcare provider about drinking alcohol while taking Norpramin.
  • Norpramin may not be safe for use during pregnancy. Talk with your healthcare provider about the benefits and risk of using the medicine during pregnancy (see Desipramine and Pregnancy for more information).
  • Norpramin passes through breast milk and may cause harm to your baby. Therefore, if you are breastfeeding or plan to start breastfeeding, be sure to talk with your healthcare provider about what makes most sense for your particular situation (see Desipramine and Breastfeeding).
  • Special care should be used when taking Norpramin if you have a history of seizures, bladder problems, or glaucoma. Norpramin can make these conditions worse.
  • Talk with your healthcare provider before taking Norpramin if you have any heart problems, as Norpramin can affect the heart and its electrical system.
  • Talk with your healthcare provider before taking Norpramin if you have hyperthyroidism (overactive thyroid) or are taking thyroid medication.
  • Taking Norpramin while receiving electroshock or electroconvulsive therapy (ECT) can increase your risk of side effects. Talk with your healthcare provider about these risks.
  • Norpramin may cause a dry mouth. Sucking on hard candy, chewing gum, or melting bits of ice in your mouth can provide relief from a dry mouth.
  • Elderly people appear to be more sensitive to Norpramin, which can increase their risk of side effects (such as delirium and confusion). In these particular situations, the healthcare provider will start people on lower doses of Norpramin and monitor them more closely.
  • During treatment with Norpramin, do not treat yourself for the common cold, a cough, or allergies without first talking with your healthcare provider. Some of these medicines can increase the risk of developing Norpramin side effects.
  • Do not stop taking Norpramin without first discussing it with your healthcare provider. Stopping the medicine abruptly may increase the risk of withdrawal symptoms (see Norpramin Withdrawal).
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