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Norpramin Uses

How Norpramin Works

Norpramin is a tricyclic antidepressant. Tricyclic antidepressants are an older group of medications that have been used to treat depression for many years. Even though Norpramin has been around for a long time, it is not entirely clear how it works. Norpramin affects several chemicals in the brain, including serotonin and norepinephrine.

Norpramin Use in Children and Teens

Norpramin is not recommended for use in people under 18 years old, as it has not been thoroughly studied in children or teens. Antidepressants have been shown to increase the risk of suicidal thinking and behavior in short-term research studies involving children and teenagers (see Desipramine and Suicide for more information on the risks of suicide with Norpramin). You should talk with your healthcare provider about treatment options for childhood or teen depression.

Off-Label Norpramin Uses

On occasion, your healthcare provider may recommend Norpramin for treating something other than depression. This is called an "off-label" use. At this time, there are several off-label Norpramin uses. Following are some of the conditions that can be treated off-label with Norpramin:
  • Chronic pain: Norpramin works best for chronic pain that is nerve-related, such as nerve pain from having shingles (including postherpetic neuralgia).
  • Anxiety disorder: Many antidepressants (including Norpramin) are used to treat anxiety disorders.
  • Bedwetting: Norpramin has been used to help people stop bedwetting.
  • Attention deficit hyperactivity disorder (ADHD): Norpramin can be used to treat ADHD, especially if other ADHD medications cause side effects or have not been effective.
  • Fibromyalgia: Norpramin has been used to treat pain and other symptoms of fibromyalgia.
  • Migraine headaches: Norpramin can be used on a daily basis to prevent migraine headaches. However, it is not effective for treating a migraine headache once it starts.
  • Treatment for bulimia: Norpramin has been found to improve bulimia symptoms, including binge eating and vomiting.
  • Smoking: Norpramin is sometimes used to help people quit smoking.
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Norpramin (Desipramine)

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