Norpramin Drug Interactions

Among the drugs that may potentially interact with Norpramin are anticholinergic medications, arrhythmia medications, and benzodiazepines. Norpramin drug interactions can increase your risk of side effects such as drowsiness or a dangerous arrhythmia called QT prolongation, among other things. Make sure to talk with your pharmacist or healthcare provider about any drug interactions with Norpramin that may apply to you.

 

Norpramin Drug Interactions: An Introduction

Norpramin® (desipramine hydrochloride) can potentially interact with many other medicines. Some of the medicines that may lead to Norpramin drug interactions include:
 
  • Alcohol
     
  • Anticholinergic medications, including:

 

 

  • Arrhythmia medications, including:

 

    • Amiodarone (Cordarone®)
    • Disopyramide (Norpace®)
    • Dofetilide (Tikosyn®)
    • Flecainide (Tambocor®)
    • Ibutilide (Corvert®)
    • Propafenone (Rythmol®)
    • Quinidine
    • Sotalol (Betapace®)

 

  • Barbiturates, including:

 

    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)

 

  • Benzodiazepines, including:

 

 

 

 

  • Phenothiazine medications, including:

 

 

 

 

  • Thyroid medications, including:

 

 

 

 

(Norpramin Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;