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Narcan Toxicity

Narcan® (naloxone hydrochloride) is prescribed to reverse the effects of opioids and to treat or diagnose an opioid overdose. Although it is possible to take too much Narcan, the toxicity effects are not entirely known.
There are no reported cases of an overdose on Narcan. Also, the drug is usually injected, as it is not absorbed well into the bloodstream when taken by mouth. Therefore, it is unlikely that it would cause problems if swallowed in high doses.
If high doses of Narcan are given, potential symptoms may include:
  • Nausea
  • Abdominal (stomach) pain.
Because this drug is normally processed and removed quickly by the body, any overdose symptoms that do occur would usually subside within a couple of hours.
(Click Narcan Overdose for a more in-depth look at possible symptoms of Narcan toxicity, including information on the steps your healthcare provider may take to help avoid these problems.)
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