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Narcan Dosage

Your healthcare provider will recommend a dose of Narcan based on several factors, such as your age, the reason you are receiving the medicine, and how you respond to it. This medication is given as an injection in a vein, a muscle, or under the skin. If necessary, you may need repeat doses every two to three minutes.


An Introduction to Dosing With Narcan

The dose of Narcan® (naloxone hydrochloride) your healthcare provider recommends will vary, depending on a few factors, including:
  • Your age
  • Your weight (for children)
  • The reason you are receiving the medication
  • How you respond to it. 
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

What Is the Recommended Narcan Dosage?

In general, dosages of Narcan can vary significantly from person to person. Your healthcare provider will choose the best amount for you based on your individual situation.
Usual doses of Narcan in adults following an opioid overdose can range from 0.4 mg to 2 mg. Because the effects of Narcan may be shorter than those of some opioids, repeated doses may be needed. These can occur every two to three minutes, if necessary.
Smaller doses are usually needed to reverse respiratory depression (slow and shallow breathing) after surgery and can range from 0.1 mg to 0.2 mg, every two to three minutes until a person is adequately alert and breathing.
Usual amounts of Narcan for reversing an opioid overdose in children are based on body weight. Specifically, the initial recommended dose is 0.01 mg per kg body weight (about 0.0045 mg per lb). If the first dose does not seem adequate, a larger, 0.1 mg per kg (about 0.045 mg per lb) dose may be given if needed. 
The usual Narcan dosage for reversing respiratory depression in children after surgery is 0.005 mg to 0.01 mg every two to three minutes.
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Narcan Medication Information

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