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Drug Interactions With Molindone

Certain medications may cause drug interactions with molindone, including narcotics, barbiturates, and antidepressants. Taking these drugs with molindone can increase your risk of developing serious side effects, such as drowsiness, confusion, or difficulty breathing. Make sure to tell your healthcare provider about all medications you are taking -- both prescription and non-prescription -- to help prevent drug interactions with molindone.

As of January 2010, the manufacturer of molindone has decided to stop making this medication. It is predicted that all current supplies will be depleted by June 2010. All people taking molindone should talk with their healthcare providers immediately about switching to a different medication.

Drug Interactions With Molindone: An Overview

Molindone hydrochloride (Moban®) can potentially interact with a number of other medicines. Some of the medicines that may lead to molindone drug interactions include:
  • Alcohol
  • Anesthetics
  • Antidepressant medications
  • Barbiturates, including:


    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)


  • Benzodiazepines, including:



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