Methylphenidate ER Oral Suspension
You should talk with your healthcare provider prior to taking this medication if you have:
- Heart problems of any kind, including heart disease, heart defects, or a heart arrhythmia (abnormal heart rhythm)
- High blood pressure
- A mental health or psychiatric problem, such as depression, bipolar disorder, or a psychotic disorder
- A family history of depression, bipolar disorder, or suicide
- A history of drug or alcohol abuse or dependence
- Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Quillivant XR and Pregnancy)
- Breastfeeding (see Quillivant XR and Breastfeeding).
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Methylphenidate ER Oral Suspension to learn more, including information on who should not take the drug.)
Methylphenidate ER oral suspension is a stimulant medication. While stimulants can cause hyperactivity, they appear to have a calming effect when used in the doses for ADHD. The exact way methylphenidate ER oral suspension produces a calming effect is unknown. What is known is that the medication affects certain chemical messengers in the brain known as neurotransmitters.
More specifically, methylphenidate ER oral suspension acts on the neurotransmitters dopamine and norepinephrine. Having too little of these neurotransmitters in certain areas of the brain is thought to lead to inattention, hyperactivity, and impulsive behavior -- the core symptoms of ADHD.
Methylphenidate ER oral suspension works by increasing the amount of dopamine and norepinephrine in certain areas of the brain. This increase in dopamine and norepinephrine would be expected to cause hyperactivity and overstimulation; however, in people with ADHD (who may not have enough dopamine and norepinephrine), increasing dopamine and norepinephrine can improve focus and reduce hyperactive and impulsive behaviors.