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Methadone Dosage

General Information on Dosing With Methadone

Some considerations for people taking methadone include the following:
  • This medication comes in the form of tablets, oral dispersible tablets, an oral solution (liquid), or injections. It is usually taken one to three times daily.
  • Try taking this medication with food if it seems to bother your stomach.
  • The dispersible tablets must be mixed in 120 mL (4 ounces) of water, orange juice, Tang®, citrus flavors of Kool-Aid® or other acidic fruit beverages prior to taking them. These particular tablets should not be swallowed whole or chewed. Although the methadone in the tablet will fully dissolve, some of the inactive ingredients in the tablets may not dissolve completely.
  • For the medication to work properly, it must be taken as prescribed. Do not increase your dosage without your healthcare provider's approval. Do not suddenly stop taking methadone, especially if you have taken it regularly for more than several weeks (see Methadone Withdrawal).
  • If you are unsure about anything related to your methadone dose, please talk with your pharmacist or healthcare provider. Do not stop taking the drug without first discussing it with your healthcare provider.
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