Mellaril Drug Interactions (Cont.)

 

QT Prolonging Medications
Since Mellaril can cause QT prolongation, it should not be combined with other medications that also prolong the QT interval. These medications include but are not limited to:
 

 

    • Ciprofloxacin (Cipro®, Cipro XR®)
    • Clarithromycin (Biaxin®, Biaxin XL®)
    • Erythromycin (Ery-Tab®)
    • Gemifloxacin (Factive®)
    • Levofloxacin (Levaquin®)
    • Mefloquine (Lariam®)
    • Moxifloxacin (Avelox®)
    • Norfloxacin (Noroxin®)
    • Ofloxacin (Floxin®)
    • Telithromycin (Ketek®)
    • Troleandomycin (Tao®)

 

  • Certain arrhythmia medications, including:

 

    • Amiodarone (Cordarone®)
    • Disopyramide (Norpace®, Norpace CR®)
    • Dofetilide (Tikosyn®)
    • Flecainide (Tambocor®)
    • Ibutilide (Corvert®)
    • Procainamide (Procanbid®)
    • Propafenone (Rhythmol®)
    • Quinidine
    • Sotalol (Betapace®)

 

  • Other phenothiazine medications, including:

 

 

 

 

(Mellaril Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;