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Marplan Drug Interactions

Cough, Cold, and Allergy Products
Taking Marplan with many cough, cold, and allergy products (including eye drops or nasal products) can increase your risk of dangerous side effects, such as high blood pressure. Most of these products should never be taken with Marplan. Always check with your healthcare provider before taking any cough, cold, or allergy products.
 
Cyclobenzaprine (Flexeril)
Do not take cyclobenzaprine and Marplan together due to the risk of dangerous side effects, such as high blood pressure or seizures. You will need to wait at least one week after stopping cyclobenzaprine before starting Marplan, and you will need to be started at a lower Marplan dosage.
 
Disulfiram (Antabuse)
There is some evidence that taking disulfiram with Marplan may cause dangerous side effects. Talk to your healthcare provider before taking these medications together.
 
Entacapone (Comtan, Stalevo)
Combining entacapone and Marplan can lead to dangerous side effects. Talk to your healthcare provider before taking these medications together.
 
Levodopa (Parcopa, Sinemet, Sinemet CR, Stalevo)
Do not take levodopa and Marplan together due to the risk of dangerous side effects, such as high blood pressure.
 
Methyldopa (Aldomet, Aldoril)
Do not take methyldopa and Marplan together due to the risk of dangerous side effects, such as high blood pressure.
 
Meperidine (Demerol)
You should not take meperidine while taking Marplan (or if you have taken Marplan within the past three weeks) due to the risk of dangerous side effects.
 
Miscellaneous Antidepressants
You should not take most antidepressants while taking Marplan (or if you have taken Marplan within the past 14 days) due to the risk of dangerous side effects.
  
Monoamine Oxidase Inhibitors (MAOIs)
Do not take Marplan and other MAOIs together due to the risk of dangerous side effects, such as high blood pressure or seizures. You will need to wait at least one week after stopping another MAOI before starting Marplan, and you will need to be started at a lower Marplan dosage.
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Marplan Drug Information

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