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Precautions and Warnings With Maprotiline

Some Warnings and Precautions With Maprotiline

Some maprotiline warnings and precautions to be aware of include:
 
  • Antidepressants (including maprotiline) may increase the risk of suicidal thinking or behavior in children, teenagers, and adults (see Depression and Suicide for more information). Therefore, if you notice any changes in symptoms or new symptoms, talk to your healthcare provider immediately. Some of these symptoms may include anxiety, hostility, agitation, panic, restlessness, hallucinations, extreme hyperactivity, and suicidal thoughts or behavior (see Maprotiline and Suicide for more information).
     
  • Before prescribing maprotiline for depression, your healthcare provider should make sure that you do not have bipolar disorder (instead of depression). Sometimes, the symptoms of bipolar disorder and depression are very similar, and maprotiline can cause problems in people with bipolar disorder.
     
  • Maprotiline may cause a worsening of schizophrenia. Discuss this with your healthcare provider before taking maprotiline.
     
  • For people taking maprotiline, caution should be used when driving, operating heavy machinery, or performing other tasks that require concentration, especially when first starting maprotiline or when switching dosages. This is because maprotiline may affect a person's mental or physical ability to perform these tasks. Make sure to understand how maprotiline affects you before performing any task that requires mental or physical concentration.
     
  • Maprotiline can interact with certain medications (see Drug Interactions With Maprotiline).
     
  • Maprotiline may enhance the effects of alcohol, barbiturates, and other medicines that affect the brain. This can lead to an increased risk for drowsiness, dizziness, suicidal thoughts, and other maprotiline overdose symptoms. Make sure to talk with your healthcare provider about drinking alcohol while taking maprotiline.
     
  • Maprotiline is considered a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are not known. Talk to your healthcare provider before using maprotiline if you are pregnant (see Maprotiline and Pregnancy for more information).
     
  • Maprotiline passes through breast milk and may cause harm to your baby. Therefore, if you are breastfeeding or plan to start breastfeeding, be sure to talk with your healthcare provider about what makes most sense for your particular situation (see Maprotiline and Breastfeeding).
     
  • Special care should be used when taking maprotiline if you have a history of seizures, bladder problems, or glaucoma. Maprotiline can make these conditions worse.
     
  • Talk to your healthcare provider before taking maprotiline if you have any heart problems, as the drug can affect the heart and its electrical system.
     
  • Talk to your healthcare provider before taking maprotiline if you have hyperthyroidism (overactive thyroid) or take thyroid medication.
     
  • Taking maprotiline while receiving electroshock or electroconvulsive therapy (ECT) can increase your risk of side effects. Talk to your healthcare provider about these risks.
     
  • Maprotiline may cause a dry mouth. Sucking on hard candy, chewing gum, or melting bits of ice in your mouth can provide relief.
     
  • The elderly appear to be more sensitive to maprotiline, which can increase their risk of side effects (such as delirium and confusion). In these particular situations, the healthcare provider will start people on lower doses of maprotiline and monitor them more closely.
     
  • If you have diabetes, when starting maprotiline or changing dosages, make sure to check your blood sugar levels more often. There have been reports of increased or decreased blood sugar levels in people who take maprotiline.
     
  • Do not treat yourself for the common cold, a cough, or allergies without first talking to your healthcare provider. Some of these medicines can increase the risk for developing maprotiline side effects.
     
  • Do not stop taking maprotiline without first discussing it with your healthcare provider.
     
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