Maprotiline Overdose: An Overview
Maprotiline hydrochloride (
Ludiomil®) is a prescription medication that has been licensed to treat
depression. It is part of a group of medications called
tricyclic antidepressants. As with all medicines, it is possible to take too much maprotiline. In fact, overdose with tricyclic
antidepressants can be very dangerous. Maprotiline overdose effects will vary depending on a number of factors, including how much maprotiline was taken and whether it was taken with any other medicines, alcohol, and/or drugs.
If you happen to overdose on maprotiline, seek medical attention immediately.
Symptoms of a Maprotiline Overdose
The effects of a maprotiline overdose may include:
- Change in heart rhythm (arrhythmia)
- Very low blood pressure (hypotension)
- Seizures
- Drowsiness
- Coma
- Rapid heart rate (tachycardia)
- Coordination problems
- Vomiting
- Blue skin
- Restlessness or agitation
- High fever
- Muscle tension
- Unusual body movements
- Dilated (wide open) pupils
- Loss of life.
Treatment for a Maprotiline Overdose
The treatment for a maprotiline overdose will vary. If the overdose was recent, healthcare provider may give certain medicines or place a tube into the stomach to "pump the stomach." Treatment may also involve supportive care. This type of care consists of treating the symptoms that occur as a result of the overdose. For example, supportive treatment options for a maprotiline overdose may include:
- Fluids through an intravenous line (IV)
- Medicines to increase blood pressure, control an irregular heart rhythm, or control seizures
- Close monitoring of the heart and lungs
- A breathing tube to help with breathing
- Other treatments based on complications that occur.
It is important that you seek medical attention immediately if you believe that you may have overdosed on maprotiline.