Drug Interactions With Maprotiline
Maprotiline Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when maprotiline is combined with any of the drugs listed above.
Maprotiline may enhance the effects of alcohol. This can lead to an increased risk for suicidal thoughts and other maprotiline overdose symptoms. Make sure to talk with your healthcare provider about drinking alcohol while taking maprotiline.
Taking maprotiline with anticholinergic medications may cause increased side effects. Talk to your healthcare provider before using these medications together, as your dosages may need to be reduced. Since some of these types of medicines are found in over-the-counter medicines, do not treat yourself for the common cold, a cough, or allergies without first talking to your healthcare provider.
Taking maprotiline with arrhythmia medications can increase your risk of a dangerous arrhythmia called QT prolongation. Also, certain arrhythmia medications can increase the level of maprotiline in your blood, increasing your risk of side effects. Talk to your healthcare provider before taking these medications together.
Taking maprotiline with barbiturates can increase the risk of side effects of both maprotiline and barbiturates, such as drowsiness or dizziness. Your healthcare provider may need to adjust your dose of these medications.
Taking maprotiline with cimetidine can increase the level of maprotiline in your blood, increasing your chance of side effects. Your healthcare provider may need to adjust your dose of these medications.