Mental Health Home > Drug Interactions With Tranylcypromine
Tranylcypromine Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when tranylcypromine is combined with any of the drugs listed above.
You should not use apraclonidine eye drops while taking tranylcypromine, due to the risk of dangerously high blood pressure (hypertension).
Strattera and tranylcypromine should not be taken together or within two weeks of each other, due to the risks of dangerous side effects.
Blood Pressure Medications
Taking tranylcypromine with high blood pressure medications can increase your risk of low blood pressure (hypotension). Always check with your healthcare provider before taking tranylcypromine with blood pressure medications.
Brimonidine (Alphagan P)
You should not use brimonidine eye drops while taking tranylcypromine, due to the risk of dangerously high blood pressure.
You should not take buspirone while taking tranylcypromine (or even if you have taken tranylcypromine within the past 10 days), due to the risk of dangerously high blood pressure.
You should use caffeine sparingly while taking tranylcypromine, due to the risk of dangerously high blood pressure. Be aware that many foods and medicines (such as "stay-awake" products and migraine products) contain caffeine.
Carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR)