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Surmontil is an antidepressant that is used for treating depression in adults. By allowing serotonin and norepinephrine to stay in the brain longer, the medication can help improve symptoms of depression. The product comes in tablet form and is usually taken one to four times a day. Side effects can include constipation, a dry mouth, and dizziness or lightheadedness.

What Is Surmontil?

Surmontil® (trimipramine maleate) is a prescription medication that is used to treat depression (also known as major depression or clinical depression).
(Click Surmontil Uses for more information, including possible off-label uses of the drug.)

Who Makes Surmontil?

Surmontil is made by Duramed Pharmaceuticals.

How Does Surmontil Work?

Surmontil belongs to a class of medications called tricyclic antidepressants. It is not entirely clear how the medicine works. However, it is known that it affects several chemicals in the brain, including serotonin and norepinephrine. It is thought that perhaps Surmontil allows these chemicals to stay in the brain longer, which can help with depression symptoms.

When and How to Take It

Some considerations for when and how to take this product include:
  • The medication comes in capsule form. When used for depression, it is usually taken by mouth one to four times daily.
  • You can take Surmontil with or without food. If it upsets your stomach, try taking it with food.
  • The drug should be taken at the same times each day to maintain even levels of the medication in your blood.
  • For the antidepressant to work properly, you have to take it as prescribed. It will not work if you stop taking it.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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