Mental Health Home > Serzone and Insomnia

There are a number of possible side effects with Serzone, and insomnia appears to be one of the most common. In clinical studies, insomnia was seen in up to 11 percent of people taking the antidepressant. If you are taking Serzone and insomnia occurs, you can try adjusting your sleep habits by keeping a regular sleep-wake cycle, avoiding exercise within two hours of bedtime, and sleeping in a dark room with a comfortable temperature.

Does Serzone Cause Insomnia?

Insomnia is one of the more common side effects of Serzone® (nefazodone hydrochloride). In studies, up to 11 percent of people reported insomnia as one of the Serzone side effects.

What Is Insomnia?

People with insomnia have one or more of the following insomnia symptoms:
  • Difficulty falling asleep
  • Waking up often during the night and having trouble going back to sleep
  • Waking up too early in the morning
  • Non-refreshing sleep.

Serzone and Insomnia: Suggestions

Some people taking Serzone find that improving their sleep habits can be an effective insomnia cure. Some tips for better sleep include:
  • Keep a regular sleep-wake cycle. Try to go to bed and wake up at the same time every day.
  • Avoid caffeine, alcohol, and nicotine in the four to six hours before bedtime.
  • Don't exercise within two hours of bedtime. Exercising five or six hours before bedtime may help you sleep more soundly.
  • Don't eat large meals within two hours of bedtime.
  • Don't nap later than 3 p.m.
  • Sleep in a dark, quiet room with a comfortable temperature.
  • If you can't fall asleep within 20 minutes, do a quiet activity somewhere else and return to bed when you're sleepy.
  • Wind down in the 30 minutes before bedtime with a relaxing pre-sleep ritual, such as a warm bath, soft music, or reading.
(Click Good Sleep Habits for more suggestions.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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