Mental Health Home > Selegiline Transdermal Patch

The selegiline transdermal patch is a prescription medicine approved for the treatment of depression in adults. By blocking the action of monoamine oxidase in the brain, the medication can help improve the symptoms of depression. The skin patch is applied once a day. Side effects can include insomnia, weight loss, and headaches.

What Is the Selegiline Transdermal Patch?

The selegiline transdermal patch (Emsam®) is a prescription medication that is used to treat depression (also known as major depression or clinical depression). It is currently the only skin patch that is approved to treat depression.
(Click What Is the Selegiline Transdermal Patch Used For? for more information on what the selegiline transdermal patch is used for, including possible off-label uses.)

Are There Side Effects?

As with any medicine, there are possible side effects with the selegiline transdermal patch. However, not everyone who uses the patch will experience side effects. In fact, most people tolerate it well.
When side effects do occur, they are often minor and either require no treatment or can easily be treated by your healthcare provider. Serious side effects are less common.
Some of the side effects of the selegiline transdermal patch include:
(Click Side Effects of the Selegiline Transdermal Patch to learn about specific side effects of the patch, including some of the more serious side effects that you should report to your healthcare provider. You can also read about other possible side effects by going to:
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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