Mental Health Home > SAM-e
SAM-e is a molecule that occurs naturally in the body. Although the body can make it using amino acids, it is also available in the form of dietary supplements. Studies suggest that SAM-e supplements may be effective for treating depression, arthritis, and intrahepatic cholestasis. Side effects that have been reported with supplements include insomnia, nausea, diarrhea, and gas.
- AIDS-related myelopathy (a spine and nerve disorder associated with AIDS)
- Intrahepatic cholestasis (a decreased ability of the liver to secrete bile, often caused by pregnancy or other conditions)
- Attention deficit hyperactivity disorder (ADHD).