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Paliperidone is a medication that can be used for the treatment of schizophrenia and schizoaffective disorder in adults. Although the medicine is not a cure for schizophrenia, it can help control symptoms and prevent them from returning. Paliperidone tablets are available by prescription and are generally taken once a day in the morning. Drowsiness, headaches, and a rapid heart rate are some of the side effects that have been reported with this medication.

What Is Paliperidone?

Paliperidone (Invega®) is a prescription medication that is used to treat schizophrenia and schizoaffective disorder.
(Click What Is Paliperidone Used For? for more information on the drug's uses, including possible off-label uses.)

Side Effects of Paliperidone

As with any medicine, there are possible side effects with paliperidone. However, not everyone who takes the medication will experience side effects. In fact, most people tolerate the drug well. When side effects do occur, in most cases they are minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
Common side effects of paliperidone include, but are not limited to:
  • Headaches
  • A rapid heart rate (tachycardia)
  • Drowsiness
  • Feelings of internal restlessness or jitteriness.
(Click Paliperidone Side Effects to learn about specific side effects of paliperidone, including some of the more serious side effects that you should report to your healthcare provider.)
You can also read about possible paliperidone side effects by clicking on:
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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