Mental Health Home > Selegiline Transdermal Patch (Emsam)

If you have been diagnosed with clinical depression, your healthcare provider may recommend a product called the selegiline transdermal patch (Emsam®). This medication belongs to a class of drugs known as monoamine oxidase inhibitors (MAOIs). It works by increasing the amount of monoamines in the brain, which improves communication between brain cells. To use this medication, apply a new patch to the skin of the upper torso, upper thigh, or outer arm once daily.
MAOIs such as the selegiline transdermal patch are known to interact with several foods and drugs. In some cases, the interactions can be dangerous. In order to use this product safely, you must commit to avoiding many medications, including many nonprescription drugs. Common side effects include:
(To learn more about this product, including who makes it, other safety precautions, and what to do in cases of overdose, click Selegiline Transdermal Patch.)
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Last reviewed by: Arthur Schoenstadt, MD
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