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Mellaril is a medication that is used for treating schizophrenia in adults and children who have not responded well to other treatments. While the drug cannot cure schizophrenia, it can help control symptoms. The medication, which is available by prescription, comes in tablet form and is usually taken two to four times daily. Possible side effects include drowsiness, constipation, and a dry mouth.

What Is Mellaril?

Part of a group of drugs known as "typical antipsychotics," Mellaril® (thioridazine) is a prescription medicine that has been licensed to treat schizophrenia in people who have not responded well to other antipsychotic medications.

Who Makes It?

Mellaril was originally manufactured by Novartis Pharmaceuticals. Although brand-name Mellaril is no longer being made, generic Mellaril is still available. The generic version is manufactured by several different companies.
(Click Mellaril Uses for more information on what the medication is used for, including possible off-label uses.)

How Does Mellaril Work?

Mellaril belongs to a group of medications called typical (or first-generation) antipsychotic medications. In particular, it is part of a group of medications called phenothiazines. It is not entirely known exactly how Mellaril works. However, it is known that the drug blocks or lessens the effects of dopamine, a chemical in the brain. Dopamine may be elevated in people with schizophrenia.
This medication is not a cure for schizophrenia. It only helps to control symptoms (see Symptoms of Schizophrenia).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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