Mental Health Home > Marplan Warnings and Precautions
Before taking Marplan, warnings and precautions to be aware of include things such as an increased risk for suicidal thoughts or behavior with the drug, potentially lethal food and drug interactions, and the danger of a life-threatening increase in blood pressure. It is also important to tell your healthcare provider about any medical conditions you might have, such as heart disease, high blood pressure, or seizures, as well as any medications you are taking.
Marplan: What Should I Tell My Healthcare Provider?You should talk with your healthcare provider prior to taking Marplan® (isocarboxazid) if you have:
- Heart disease
- High blood pressure (hypertension)
- A history of stroke, transient ischemic attack (TIA or "mini-stroke"), or other bleeding in the brain (such as a subarachnoid hemorrhage)
- Pheochromocytoma, a certain type of adrenal tumor
- Have an upcoming surgery or procedure involving general or local anesthetics
- Liver disease, including liver failure or cirrhosis
- Frequent headaches
- Bipolar disorder or a family history of bipolar disorder (also known as manic depression)
- A history of suicide attempts or suicidal thoughts
- Kidney problems, including kidney failure (renal failure)
- Seizures or epilepsy
- An upcoming radiology procedure
- An overactive thyroid (hyperthyroidism) or are taking thyroid medications
- Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you:
- Are pregnant or thinking of becoming pregnant
- Are breastfeeding
- Drink alcohol regularly.
Make sure to tell your healthcare provider about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.