Mental Health Home > Iloperidone

Drug Interactions

Iloperidone can potentially interact with several other medications (see Drug Interactions With Iloperidone).

Overdose Information

During studies, accidental overdoses of this medication caused symptoms such as drowsiness, low blood pressure, or a rapid heart rate. If you happen to overdose on this product, seek immediate medical attention.
(Click Fanapt Overdose for more information.)

What Should I Do If I Miss a Dose of Iloperidone?

If you forget to take your dose, take the missed dose as soon as you remember. If it is almost time for your next dose, simply skip the missed dose and continue with your regular schedule. Do not take a double dose of the medication.

How Does It Work?

Iloperidone belongs to a group of medications called atypical (or second-generation) antipsychotic medications. It is not entirely known how the drug works for the treatment of schizophrenia. However, it is known that iloperidone blocks or lessens the effects of certain chemicals in the brain. These brain chemicals (such as dopamine and serotonin) may be elevated in people with schizophrenia.

Clinical Effects

This medication has been thoroughly evaluated in clinical studies. These studies compared iloperidone to a placebo (a "sugar pill" that does not contain any active ingredients) or other antipsychotic medications to treat acute schizophrenia.
Although this medication was more effective than a placebo, it seemed to be less effective (at least early on) compared to certain other antipsychotics. It is thought that this is probably due to the fact that iloperidone must be started at a low dose (and the dosage must be slowly increased).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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