Glutamine supplementation by IV may be useful for preventing problems in people who are critically ill (such as after severe physical trauma) and may aid in recovery after certain types of surgery. Oral supplementation may be useful for helping people with HIV or AIDS gain weight and may decrease the risk of mouth sores in people undergoing chemotherapy. It is not known if glutamine is effective for most other uses.
There are no clear guidelines for a safe and effective glutamine dose for most uses. Because it is a non-essential amino acid, there is no Recommended Dietary Allowance (RDA) for glutamine. Be sure to follow the specific instructions on your particular product.
Most people generally tolerate glutamine well, but many people find the grittiness of glutamine powder to be rather unpleasant. Although there are several theoretical side effects that are possible with glutamine, most studies have indicated that glutamine is unlikely to cause significant side effects.
(Click Glutamine Side Effects to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Jellin JM, editor. Pharmacist's Letter/Prescriber's Letter Natural Medicines Comprehensive Database Web site. Available at: http://naturaldatabase.com/. Accessed March 26, 2008.
Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrates, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (Macronutrients). Washington, DC: National Academy Press, 2005. Available at: http://books.nap.edu/openbook.php?record_id=10490&page=R1. Accessed March 26, 2008.
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