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It is not known whether it is safe to use glutamine (L-glutamine) supplements during pregnancy. A normal dietary intake of glutamine through foods is safe for pregnant women, but higher levels due to supplementation could cause problems. Pregnant women should not take glutamine until more information is available. If you are taking glutamine and pregnancy occurs, talk to your healthcare provider about the potential risks.

An Overview of Glutamine and Pregnancy

Glutamine (also known as L-glutamine) is an amino acid found in protein-rich foods and also used in dietary supplements. It is also produced naturally by the human body. As with most dietary supplements, it is not clear at this time whether glutamine supplements are safe for use during pregnancy. Therefore, it is a good idea to check with your healthcare provider before taking any supplements that contain glutamine during pregnancy.

Is Glutamine Safe for Pregnant Women?

Although a normal dietary intake of glutamine (through foods) is safe for pregnant women, it is not known whether glutamine supplements are equally safe.
There are no reliable studies that show that glutamine is safe (or unsafe), since glutamine supplementation has not been adequately studied in any pregnant women. It might seem logical that glutamine supplements would be perfectly safe for pregnant women, since glutamine is just an amino acid that is found in many foods (and produced naturally by the human body). However, it cannot be assumed that glutamine supplementation is as safe as a normal dietary intake of glutamate. Perhaps the higher levels due to supplementation could cause problems, or perhaps the glutamine in supplements is slightly different from the glutamine found in foods.
It is also possible that your glutamine supplements may contain contaminants or other ingredients that are not safe for use in pregnancy. Until more information is available, it is probably wise to wait until after pregnancy to try glutamine supplements.
If you are pregnant, it is always a good idea to ask your healthcare provider before taking any medication or supplement. You and your healthcare provider can consider the possible risks and benefits of using glutamine in your particular situation, as well as any other treatment alternatives.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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