Mental Health Home > Precautions and Warnings With Desvenlafaxine

Who Should Not Take Desvenlafaxine?

You should not take desvenlafaxine if you:
  • Are allergic to desvenlafaxine, Pristiq, or any inactive components used to make the medication. Your healthcare provider or pharmacist has a list of the inactive ingredients.
  • Are allergic to venlafaxine (Effexor®, Effexor® XR), a closely related medication.
  • Are taking linezolid (Zyvox®) or intravenous methylene blue. Desvenlafaxine should not be started in people taking linezolid or IV methylene blue, but a person already taking desvenlafaxine may be given linezolid or methylene blue, if absolutely necessary, and only with very careful monitoring and only if desvenlafaxine is stopped during treatment.
  • Have taken a monoamine oxidase inhibitor (MAOI) within the past two weeks. Also, you should not take an MAOI if you have taken desvenlafaxine within the last seven days. MAOIs include:

Precautions and Warnings With Desvenlafaxine: Final Thoughts

There are a number of situations in which desvenlafaxine should not be taken, as well as several precautions and warnings people should be aware of before starting the medication. However, it is possible that not all of the warnings or precautions were discussed in this article. Therefore, you should talk with your healthcare provider about the specific precautions and warnings with desvenlafaxine that may apply to you.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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