Mental Health Home > Drug Interactions With Desvenlafaxine

People are generally recommended to avoid drinking alcohol while taking desvenlafaxine. Drug interactions may also occur if the depression medication is taken with cimetidine, haloperidol, monoamine oxidase inhibitors, or nonsteroidal anti-inflammatory drugs, among other things. To help prevent drug interactions with desvenlafaxine, tell your healthcare provider about all other medicines you are taking before beginning treatment.

An Introduction to Drug Interactions With Desvenlafaxine

Desvenlafaxine succinate (Pristiq®) can potentially interact with a number of medicines. Some of the medicines that can lead to drug interactions with desvenlafaxine include:
  • Alcohol
  • Medications that "thin" the blood (such as anticoagulant and antiplatelet drugs), such as:
      • Alteplase (Activase®)
      • Reteplase (Retavase®)
      • Streptokinase (Streptase®)
      • Tenecteplase (TNKase®)
    • Monoamine oxidase inhibitors (MAOIs), such as:
    Written by/reviewed by:
    Last reviewed by: Kristi Monson, PharmD;
    Last updated/reviewed:
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