Mental Health Home > Bupropion XL
How Does Bupropion XL Work?Bupropion XL is a norepinephrine and dopamine reuptake inhibitor, or NDRI for short. NDRIs, such as bupropion XL, affect specific chemicals within the brain known as norepinephrine and dopamine. These are two of several chemicals used to send messages from one nerve cell to another.
- Wellbutrin (bupropion hydrochloride), a short-acting version
- Wellbutrin SR® (bupropion SR), a sustained-release version (taken twice a day)
- Aplenzin™ (bupropion hydrobromide), taken once a day
- Zyban® (bupropion SR), a sustained-release version used for smoking cessation.