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Atomoxetine Dosing for ADHD in Adults

For adults (and children or teens weighing more than 154 pounds), atomoxetine should be started at 40 mg once daily (or 20 mg twice daily). After at least three days, your healthcare provider can increase your atomoxetine dose to 80 mg once daily (or 40 mg twice daily). If necessary, your healthcare provider may increase your atomoxetine dose to 100 mg (total per day) after two to four weeks. The maximum dose of atomoxetine is 100 mg per day.
People with liver problems, including liver failure or cirrhosis, will need to take lower doses of atomoxetine because the liver helps to remove atomoxetine from the blood. Also, certain medications can increase the amount of atomoxetine in the blood. The dose of atomoxetine should also be lower for people who are taking certain medications that may interact with atomoxetine (see Drug Interactions With Atomoxetine).

General Information on Dosing With Atomoxetine

Some considerations for people taking atomoxetine include:
  • The medication should be taken at the same time(s) each day.
  • Atomoxetine should be taken in the morning. If taken twice daily, the second dose is usually taken in the late afternoon or early evening.
  • If you do not take your atomoxetine as scheduled, take your missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take double the dose at one time.
  • Your atomoxetine dose can be taken with or without food. If the medication bothers your stomach, try taking it with food.
  • For the medicine to work properly, you have to take it as prescribed. Atomoxetine will not work if you take it in a way other than how your healthcare provider has prescribed it.
  • If you are unsure about anything related to your dosage or atomoxetine dosing in general, please talk with your doctor, nurse, or pharmacist. Do not stop taking the medication without first discussing it with your healthcare provider.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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