Unlike some other schizophrenia medications, lurasidone has simple and straightforward dosing guidelines. For example, the recommended starting amount for schizophrenia treatment is 40 mg a day. If necessary, your healthcare provider may increase this dose. Lurasidone can be taken at any time during the day, but if you find that it causes drowsiness, you may prefer to take it at bedtime.
The dose of lurasidone hydrochloride (Latuda®) your healthcare provider recommends will vary, depending on a number of factors, including:
- The condition being treated
- How you respond to lurasidone
- Other medications you may be taking
- Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
The dosing for some schizophrenia medications can be complicated, involving extensive "titrations," during which a low starting dose is gradually increased to a more effective one. However, the dosing for lurasidone is simple and straightforward, with no confusing titration needed.
The recommended starting lurasidone dosage is 40 mg once daily. Your healthcare provider may increase this up to a maximum of 160 mg once a day, but only if necessary, since 40 mg daily is adequate for many people. If you have moderate or severe kidney or liver disease, or are taking certain other medications (see Drug Interactions With Lurasidone), you might be started with a lower dosage (20 mg a day), and a lower maximum dosage may be recommended (either 40 mg or 80 mg, depending on your particular situation).
It is important to take your lurasidone dosage with food, since taking the drug on an empty stomach reduces the amount that is absorbed into the body. The content of the meal or snack does not matter, but it should consist of at least 350 calories.