Loxapine

Loxapine is a drug that is licensed to treat schizophrenia. Known as a typical antipsychotic, the drug is thought to work by blocking or lessening the effects of dopamine in the brain. It comes in capsule form and is typically taken two to four times a day. Possible side effects of loxapine include unusual body movements, muscle tension, and overactive reflexes.

 

What Is Loxapine?

Loxapine (Loxitane®) is a prescription medicine known as a "typical antipsychotic" that has been licensed to treat schizophrenia.
 

Who Makes Loxapine?

Loxapine is manufactured by Watson Pharmaceuticals.
 
(Click What Is Loxapine Used For? for more information, including possible off-label uses.)
 

How Does Loxapine Work?

Loxapine is one of several medications known as typical (or first-generation) antipsychotic medications. It is not entirely known exactly how the drug works. However, it is known that loxapine blocks or lessens the effects of dopamine, a chemical in the brain, that may be elevated in people with schizophrenia.
 
Loxapine is not a cure for schizophrenia. It only helps to control symptoms (see Symptoms of Schizophrenia).
 

When and How to Take Loxapine

The following are some general considerations for when and how to take loxapine:
 
  • The medication comes in capsule form. It is usually taken by mouth two to four times a day.
     
  • You can take loxapine with or without food. If the medication bothers your stomach, try taking it with food.
     
  • Loxapine should be taken at the same time(s) each day to maintain an even level in your blood.
     
  • For loxapine to work properly, it must be taken as prescribed. The medication will not work if you stop taking it.
 
(Loxapine Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;